男性非淋菌性尿道炎病人支原体检测及其药敏分析

Mycoplasma detection and drug resistance in male patients with nongonococcal urethrifis

目的了解男性非淋菌性尿道炎（NGU）病人支原体感染及耐药情况。方法支原体检测使用珠海丽珠公司支原体分离鉴定、计数、药敏试剂盒。结果304例病人，支原体感染70例，总感染率为23．1％，其中解脲脲原体（Uu）单项阳性64例（21．0％），人型支原体（Mh）单项阳性6例（1．9％），Uu和Mh混合阳性20例（6．5％）。支原体对强力霉素、美满霉素的耐药率最低，其次为氧氟沙星、左旋氧氟沙星、司帕沙星。结论非淋菌性尿道炎的主要病原支原体是解脲脲原体和人型支原体，强力霉素、美满霉素应作为治疗男性支原体非淋菌性尿道炎的首选药物。

Objective To unveil the status of mycoplasmal infections and antimicrobial resistances in male patients with nongon0eoceal urethritis. Methods Mycoplasma was detected by myeoplasmal culture and drug resistance was determined by a kit produced by LIVZON Pharmaceutical Group Inc. in male patients with nongonococeal urethritis. Results Among 304 urethral specimen tested, 70 （23.1%） were positive for Mycoplasma species： 64 （21.0%）, 6 （1.9%）, and 20 （6.5%） were positively for Ureaplasma urealytieum （Uu）, Myeoplasma hominis （Mn） and both, respectively. Drug resistance rates to doxyeyeline and minocyeline were the lowest among common anti-myeoplasmal drugs tested. Conclusions Uu and Mn are the major Mycoplasma species detected and doxyeyeline or minoeyeline should be the first choice of drugs for treating non-gonococcus urethritis.