原发性肝癌患者血清CA199和TSGF联检的临床意义

Clinical Significance of Combined Determination of Serum CA199 and Tumor Specific Growth Factor (TSGF) Contents in Patients with Primary Hepatic Carcinoma

目的:探讨了原发性肝癌患者血清TSGF和CA199水平的变化及其临床意义。方法:应用免放法测定33例原发性肝癌患者血清CA199含量,光电比色法测定TSGF含量,并与35名正常健康人作比较。结果:原发性肝癌患者血清TSGF和CA199水平均非常显著地高于正常人组(P<0.01)且与血清AFP水平呈明显的正相关。结论:测定原发性肝癌患者血清TSGF和CA199水平对临床的诊断和治疗均有十分重要的临床价值。

Objective To investigate the clinical significance of the changes of serum TSGF and CA199 contents in patients with primary hepatic carcinoma. Methods Serum CA199 （with IRMA） and TSGF （with biochemistry method） contents were determined in 33 patients with primary hepatic carcinoma and 35 controls.Results Serum CA199 and TSGF contents were significantly higher in patients with primary hepatic carcinoma than those in controls （P 〈0.01） and their levels were significantly positively correlated with those of serum AFP. Conclusion Determination of serum TSGF and CA199 contents was of clinical diagnostic value in patients with primary hepatic carcinoma.