摘要
目的:探讨治疗难治性复发性急性白血病(AL)的有效方案.方法:27例难治性复发性AL用吡柔比星(THP)、足叶乙甙(VP16)、安吖啶(AMSA)、阿糖胞苷(Ara-C)组成的TEAA方案治疗.用法:THP 10 mg/d,静脉滴注,第1~3天;VP16 100mg/d,静脉滴注,第1~4天,AMSA75mg/d,第1~3天,静脉滴注;Ara-C200mg/d,第1~7天,静脉滴注.结果:在1~3个疗程(平均1.4疗程,32.5 d后)完全缓解16例(59.3%),部分缓解(PR)5例(18.5%),总有效率为77.8%.结论:TEAA方案是治疗难治性复发性AL较有效的方案.
Objective: To explore the therapeutic protocol for refractory and relapsed acute leukemia(AL). Methods: 27 cases of refractory and relapsed AL were treated with TEAA(THP, VP16, AMSA, Ara-C) regimen, which consisted of THP10mg/d(d1~3), VP16 100mg/d(d1~4), AMSA75mg/d(d1~3), intravenous drip, Ara-C200mg/d(d1~7), intravenous drip. Results: 17 patients(59. 3%) achieved complete remission, 5 patients( 18. 5%) achieved partial remission, overall effective rate was 77. 8%. Conclusions: TEAA regimen in treatment of refractory and relapsed AL is an effective means.
出处
《内科急危重症杂志》
2005年第4期176-177,共2页
Journal of Critical Care In Internal Medicine
关键词
吡柔比星
足叶乙甙
安吖啶
阿糖胞苷
急性白血病
难治及复发性
Pirarubicin Etoposide Amsacrine Cytosine arabinoside Acute leukemia refractory and relapse fractory and relapse