肺癌患者血清某些微量元素的检测分析

SOME SERUMAL TRACE ELEMENTS TEST AND ANALYSIS ON PATIENTS WITH LUNG CANCER

本文应用原子吸收法（ＡＡＳ）检测５０例正常健康人和１４３例肺癌患者血清铜（Ｃｕ）、锌（Ｚｎ）、铁（Ｆｅ）、镁（Ｍｇ）、铜（Ｃｄ）、硒（Ｓｅ）六种微量元素。结果，肺癌组血清Ｃｕ、Ｆｅ、Ｍｇ、Ｃｄ升高，Ｚｎ、Ｓｅ降低，与健康组比较，均有显著性差异（Ｐ＜０．０１～０．０２５）。提示：患者体内存在低锌高镉、低锌高铜、低硒高镉的拮抗作用。亦可作为肺癌诊断和治疗的一项参考指标。

Six serumal trace elements Cuprum(Cu ),Zinc(Zn ),Ferrum(Fe),Magne-sium(Mg),Cadmium(Cd),Selenium (Se ),were tested on 50 healthy individuals and 143 pa-tients with lung cancer. The result showed that patients with lung cancer had a increasedserumal level of Cu, Fe, Mg, Cd and a decreased level of Zn,Se. Compared with healthygroup, the difference was significant(P<0. 01-0.025 ).This indicates that antagonism be-tween low Zn and high Cd,low Zn and high Cu,low Se and high Cd exists.It is thought of arefererice in diagnosis and treatment of lung cancer.