108例病毒性肝炎患者血清补体的研究

Study of Serum Complement in 108 Patients with Virosis Hepatitis

报告１０８例病毒性肝炎患者血清总补体（ＣＨ＿（５０））和Ｃ＿３值的检测结果：急性肝炎的ＣＨ＿（５０）为６８．４±６．１３单位／ｍｌ，Ｃ＿３为１３０．２±６．６７ｍｇ％，均高于正常组（ＣＨ＿（５０）为４８．５±５．７５单位／ｍｌ，Ｃ＿３为１０２±５ｍｇ％），Ｐ＜０．０１；其他类型的肝炎患者组的补体均低于正常组，Ｐ＜０．０１．补体的含量与Ｔ细胞花环（Ｅｔ花环）呈中度相关，与ＧＰＴ呈高度相关，因此测定ＣＨ＿（５０）和Ｃ＿３可作为衡量患者机体免疫功能和判断病毒性肝炎预后的指标之一。

Serum total complement and C_3 in 108 patients with viosis hepatitis were determined. The resultsshowed that CH_(50) and C_3 in acute hepatitis were 68.4±6.13u/ml and 130.2±6. 67mg% respectively,andboth were significantly higher than controls (CH_(50): 48.5±5. 75u/ml,C_3:102±5mg%).Other types of hepati-tis patients were all significantly lower than controls(P<0.01).The amount of CH_(50) and C_3 in each group ismoderately related to E-rosettes(r=0. 63 and r=0. 58 respectively),and is highly related to GPT(r=0.98)。Thus,the amounts of CH_(50) and C_3 are one of the indexes that can judge the immunological function and prog-nosis in patients with virosis hepatitis.