摘要
自草药瓜子金(Polygala japonica Houtt)地上部分又分离得到两种皂甙,即瓜子金皂甙丙和皂甙丁,它们的分子式均为 C_(42)H_(68)O_(15),为同分异构物。两者酸水解均得瓜子金皂甙元和 D-葡萄糖,但碱水解时,只有皂甙丁可被水解,产物和酸水解相同。经~1HNMR,^(13)CNMR,MS 推定它们的结构式,瓜子金皂甙丙为3-O-[β-D-葡萄吡喃糖(1→2)-β-D-葡萄吡喃糖]瓜子金皂甙元;而瓜子金皂甙丁为28-O-[β-D-葡萄吡喃糖(1→2)-β-D-葡萄吡喃糖]瓜子金皂甙元。上述两种皂甙均为新化合物。
Two new triterpene saponins C and D have been isolated from the aerial parts of Poly- gala japonica Houtt.Their molecular formulas:C_(42)H_(68)O_(15) were structural isomers of each other.Acid hydrolysis of the two saponins all produced a sapogenin (2a,3a,24-trihydroxyo- lean-12-ene-28-oic acid) and D-glucoses.But only the saponin D could be hydrolyzed in the .alkaline solution,the products were identical with those from acid hydrolysis.Their structu- res have been established by means of ~1HNMR,^(13)CNMR and MS as 3-O-[β-D-glucopyranosyl (1→2)[β-D-glucopyranosyl] 2a,3a,24-trihydroxyolean-12-ene-28-oic acid,28-O-[β-D-glucopy- ranosyl (1→2)-β-D-glucopyranosyl] 2a,3a,24-trihydroxyolean-12-ene-28-oic acid.
关键词
瓜子金
皂甙丙
皂甙丁
化学结构
Polygala Japonica Houtr
3-O-[β-D-glucopyranosyl (1→2)-β-D-glucopyra-nosyl] 2a,3a,24-trihydroxyolean-12-ene-28-oic acid
28-O-[β-D-glucopyranosyl (1→2)-β-D-glucopyranosyl] 2a,3a,24-trihydroxyolean-12-ene-28-oic acid
