阻塞性黄疸胆道手术中迷走反射的实验研究

Experimental Study of Vagus Reflex during Biliary Operation in Rabbits with Obstructive Jaundice

通过实验研究，对正常胆道胆囊牵拉和阻黄疸胆囊牵拉后引起的血压、心率的变化进行了比较，结果两组均无显著差异（Ｐ＞０．０５）。认为阻黄疸胆道压力增高时，迷走神经兴奋性并不强于正常组。只是由于阻黄症组心肌本身功能已减弱，在迷走神经兴奋后，较易发生心排血量减少、血压下降、心率减慢，甚至心跳骤停。故临床上对阻黄症病人可采取提高心脏的功能、增强心肌的收缩力及局部封闭等措施，以防不测。

xperimental study of vagus reflex was conducted during biliary proceduce in rabbits。The results show thatthe changes of MAP and HR in the rabbits with obstructive jaundice were similar to that in the normal rabbits,which indicates that biliary hypertension caused by biliary obstruction did not increase vagal excitability.Circulatory depression often seen clinically in the patients with obstructive jaundice is partly because of an impared cardiacfunction。To avoid serious circulatory complicatiOn,therefore,it is essentiaI to improve myocardial function in thepatients with obstructive jaundice。