青少年骨巨细胞瘤

Giant Cell Tumor in Children and Adolescents

本文回顾分析３６２例骨巨细胞瘤中３８例发生于青少年的Ｘ线表现，其发病年龄均在２０岁以下。其中２６例位于短和长管状骨，２２例的骨骺线尚未闭合，均未侵犯骨骺。所有病变均表现为溶骨性破坏，９例的皮质呈不规则破坏。３６例均有膨胀使新的皮质骨重新塑形形成其外缘。２８例病理分级属于Ⅰ级和Ⅱ级，１９例属Ⅲ级，Ⅳ级仅１例。属于Ⅰ级和Ⅱ级的２８例中除２例外均在Ｘ线片上表现为良性，Ⅲ级和Ⅳ级的１０例中，Ｘ线片看到恶性征象者仅３例。

The radiological appearance of giant cell tumor in the developing skeleton was retrospectively assessd in 38(10.5%) in 362 patients,There were all under the age of 20.26 tumors were located in short and long tubular bones with epiphyseal growth plates still open in 22 patients,the epiphysis were never involved.All lesions showed a osteolytic type of destruction;the cortex was irregularly destroyed in 9 cases,Expansile remodling of a neocortex was present in 36 patients.Most of this group patients(28 cases) had lesion of grade Ⅰand Ⅱ, 9 lesions were grade Ⅲ, and only 1 lesion was grade Ⅳ. 28 patients which had lesions of grade Ⅰ and Ⅱ, except 2 patients,all considered radiologically benign;in 10 cases of grade Ⅲ and Ⅳ,the radiological appearance were malignant only 3 cases.