摘要
对３３例足月窒息新生儿进行长程ＥＥＧ监测和定量分析，结果表明伴有中～重度ＨＩＥ及惊厥发作组背景ＥＥＧ异常率显著增加，重度异常者预后不良。重度窒息及伴有中～重度ＨＩＥ或惊厥发作组阵发性异常放电出现率显著增加。定量分析表明无或轻度ＨＩＥ患儿有轻度的睡眠周期紊乱，背景活动恶化时则可出现明显睡眠周期异常。表明新生儿窒息时的缺氧缺血性改变可导致一过性或持续性脑功能障碍，长程ＥＥＧ监测和定量分析有助于指导临床诊断治疗及判断预后。
Abstract Long term monitoring and quantitative analysis of EEG was studied in 33 full-term neonates with asphyxia.The abnormality of EEG background activity in neonates complicated with moderate and severe HIE and convulsion was obviously high,and the prognosis was poor in neonates with severe EEG abnormality.The appearance of abnormal paroxysmal discharge was apparently high in severe asphyxia associated with moderate and severe HIE and convulsion.Quantitative analysis showed sleeping cycle disorder in neonates with a mild or without HIE. When the condition became deterioted,the sleeping cycle became obviously abnormal accordingly.these findings suggested that the change in anoxia and ischernia during asphyxia might lead to transcient or persistent disturbance of the cerebral function.Long period-term monitoring and quantitative analysis of EEG are valuable tools in the guidance and judgement of the diagnosis and treatment as well as prognosis.
