^（133）Xe吸入法测定震颤麻痹脑局部区域血流量

￣(133)Xenon-inhalation technique:Measurement of regional cerebral blood flow in Parkinson’s disease.

用^（１３３）Ｘｅ吸入法测定２０例震颤麻痹及１０名正常人脑局部区域血流量（ｒＣＢＦ），病例组双半球、脑干－小脑ｒＣＢＦ均明显低于正常健康组，病例组ｒＣＢＦ值与病情程度无关，ＣＴ示弥漫性皮质萎缩、皮质下萎缩及混合性萎缩，其ｒＣＢＦ明显低于ＣＴ正常者，病例组脑动脉对ＣＯ＿２扩张反应能力差。

AbstractMeasurement of regional cerebral blood flow(rCBF)was performed with ￣(133) Xenon-inhala-tion technique in 20 patients with Parkinson’s disease and in 10 normal subjects.rCBF of both hemispheres, cerebellum and brainstem in patients was reduced more obviously than in normal sub-jects of the same age.rCBF in patients did not corre late with severity of the illness.rCBF in pa-tients with diffuse cortical atrophy , subcortical atrophy or mixed atrophy as shown by CT scans was obviously lower than in thoses patients with normal CT. Dilative capacity of cerebral arteries to CO_2 inhalation in patients’group was rather poor.