原发性震颤与帕金森震颤时手指捏合过程中的动作震颤和捏合震颤的初步研究

Tremor movement and grip tremor during finger grip in essential tremor and parkinsoniantremor

本文报道应用捏合仪及光电子运动分析技术，对ＥＴ和ＰＴ病人手指捏合过程中手震颤时ＴＭＦ、ＴＭＡ、ＧＴＦ及ＧＴＡ四项指标变化的定量研究结果：（１）两组ＴＭＦ和ＧＴＦ各项试验中变化很小；ＴＭＡ及ＧＴＡ值变化与震颤严重度相一致。（２）ＥＴ组总ＧＴＡ水平高于ＰＴ组，其变化不如ＴＭＡ显著，尤在快运动时；ＰＴ组ＴＭＡ变化通常与捏合强度成比例，运动时ＧＴＡ变化比ＴＭＡ更明显。结果提示：（１）此两震颤成分可能源自同一机制。（２）捏合时ＥＴ病人手震颤性质可能主要为手指捏合震颤，而ＰＴ病人主要为手动作震颤。对其可能的临床价值进行了讨论。

Abstract Using grip instrument in combination with optoelectronic movement analysis technique,the authors quantitatively studied the changes of 4 indicators(TMF,TMA,GTA and GTF)in 10 pa- tients. The results revealed that(1)TMF and GTF during various tests had no statistically signifi- cant changes,while TMA and GTA changes were in agreement with respective clinical tremor de- gree of severity;(2)In ET group,general GTA level was higher than that in PT group,and its changes were not so marked as TMA,especially during fast movement;(3)In PT group TMA changes usually were more obvious than that of TMA The results suggest that(1)These two tremor components may originate from the same mechanism;(2)In ET tremor property during grip might mainly be a finger grip tremor other than a finger movement tremor,while in PT,its property一a finger movement tremor.Its possible value for clinical application is briefly dis- cussed.