几丁质管桥接周围神经超微结构观察

Transmission electron-microscopy of chitin tube bridged peripheral nerve defect

采用生物材料几丁质制成的管道桥接大鼠坐骨神经缺损，术后１２周取桥接物远近端和中央部，应用透射电镜观察再生神经纤维内部结构。结果表明，再生有髓和无髓神经纤维平行排列，极性一致，相邻神经纤维共用同一髓鞘，有髓神经纤维有分支现象，髓鞘完整，板层与板层排列紧密，轴突膜与髓鞘膜紧密相邻，间质无髓神经纤维丰富。

In our study a tube made of chitin is used to bridge the defect in sciatic nerve of rat. We section the proximal, distal and intermediate parts of the tubular bridges respectively to observe the internal structures of regenerative neurofibrils under transmission electronmicroscopy twelve weeks postoperatively. The results show that the regenerative myelinated and nonmyelinated neurofibrils have parallel arrangement and the same dynamic polarity.The neighboring neurofibrils have common myelin sheathes and the myelin sheath appears complete. The lamina arrange tightly and the membrane of axon and myelin sheath neighbor compactly. Also, there are many nonmyelinated neurofibrils in the interstitium.