慢性肝病与乙型、丙型肝炎病毒感染的关系

The relation between chronic hepatopathy and infection of B and C hepatitis virus

采用酶联免疫法（ELISA）对270例慢性肝病和对照组103例非肝病患者进行了HBV标志物及抗－HCV的检测。结果显示；慢性肝病HBV感染率为85．2％，抗－HCV阳性率为23．7％，HBV和HCV双重感染率为17．8％，单纯抗－HCV阳性率为5．9％。对照组HBV感染率为14．6％，抗－HCV阳性率为5．8％。126例有输血史的慢性肝病患者抗－HCV阳性率（42．1％）明显高于144倒无输血史者（7．6％），两组差异有显著性（P＜0．01）。提示HBV感染是引起慢性肝病的主要病因，HCV次之。HCV感染与输血有密切关系。

The detections of HBV-marker (HBVM) and anti-HCV were made by enzyme Linked immunosorbent assay (ELISA) in 270 cases ill with chroric hepatopathy and 103 cases who were not hepatopaths as control group. The results showed that HBV infection rate of chrosnic hepatopathy was 85. 2 percent, the positive rate of anti-HCV was 23. 7 percent, the rate of double infection of HBV and HCV was 17. 8 percent,the simple anti-HCV positive rate was 5. 9 percent. In the control group, HBV infection rate was 14. 6 percent, the positive rate of anti-HCV was 5. 8 percent. The positive rate of anti-HCV (42. 1 percent) in 126 chronic hepatopaths who had a history of blood transfusion was obviously higher than that (7. 6 percent) in 144 cases who had no history of blood trans fusion, and There was a remarkable difference between the two groups (P<0.01 ). The results indicate that chronic hepatopathy is mainly caused by HBV infection, HCV infection gets the second place in the disease, and HCV infection has close relations with blood transfusion.