强骨珍的营养保健作用动物实验研究

ANIMAL EXPERIMENTAL STUDIES ON HEALTHY EFFECTS OF OP DAINTY

强骨珍是一种针对原发性骨质疏松症的功能性食品。实验采用１０只Ｗｉｓｔａｒ大鼠，将其分成４组，用低钙饲料、肌注地塞米松制成骨质疏松模型，用强骨珍加以治疗。实验５周后将动物处死，分别测定各组动物的股骨干重、灰重、股骨中Ｃａ、矿物质含量，心肌脂褐质含量血清、肝脏中ＬＰＯ值。此外，还进行了强骨珍的动物体外试验。实验结果表明：强骨珍能有效地提高骨干重、灰重、Ｃａ含量、矿物含量和骨密度，能抑制肝脏ＬＰＯ形成，降低心肌脂褐质含量，且能改善下丘脑一垂体一性腺轴功能。

OP Dainty is a special functional food to prevent osteoporosis,In this experiment,40 Wistar rats were divided into 4 groups. The animal medel of osteoporosis in rats was inducedby. a low calcium diet and dexamethasome. At the end of the experimental peried(5 weeks),therats were killed and the response parameters were determined,The parameters were dry weightand ash weight of the femur,calcium and mineral content in the femur,myocardium lipofuscin,lipid peroxidation(LPO) in serum and liver.The results showed that OP Dainty enhanced sig-nificantly dry weight,ash weight,calcium content and mineral content,inhibited the elevationof LPO, decreased the level of mycardium lipofuscin and regulated the function of the hypothala-mus-hypophysis-gonad axle.