新生儿体外中性粒细胞吞墨试验的临床意义

Clinical Significance of the Ink-uptaking test of PMN in Newborns

应用中性粒细胞墨汁吞噬功能试验检测３４例新生儿感染性疾病和１８例新生儿非感染性疾病及２０例正常足月产新生儿脐血。结果表明感染组的中性粒细胞吞墨指数（３４．５２９±９．３２３）及吞墨率（２４．０３５±１０．７１）均高于非感染组（１１．２１０±４．３４６、８．４０１±４．１９５，Ｐ＜０．０１）和正常对照组（１０．２５２±４．４１０、８．５３１±３．２０１．Ｐ＜０．０１）．后两者间无显著差异（Ｐ＞０．０５）．因此，简便易行的中性粒细胞吞墨试验可为了解新生儿感染提供一个实验参数。

Ink-uptaking test of PMN was done in thirty-four newborns with infectious diseases and 18 newborns with non-infections diseases and 20 normal newborns. The rate and index of phagocytosis in diseased newborns(24. 035±10. 71, 34. 529±9. 323) were higher than that of the normal newborns(8. 401 ±4. 195, 11. 20±4. 346, P<0. 01), that of the non-infectious newborns8. 531±3. 201, 11. 210±4. 346, P<0. 01). It suggests that the simple,fast ink-uptaking test of PMN may serve as a good mark to detect the presence of infectious diseases in newborns.