交感神经系统活动在扩张型心肌病心衰发病机理中作用探讨

Effect of Sympathetic System in Congestive Heart Failure from Dilated Cardiomyopathy

检测２７人次的血浆去甲肾上腺素（ＮＥ）、异丙肾上腺素敏感试验（ＩＣＤ２５）及ＬＶＥＦ、ＣＯ、ＣＩ、ＳＶ。结果示：ＮＥ与ＬＶＥＦ、ＣＯ、ＣＩ、ＳＶ呈负相关；ＩＣＤ２５与ＬＶＥＦ、ＣＯ、ＣＩ呈负相关；ＮＥ与ＩＣＤ２５呈正相关，１０例扩张型心肌病（ＤＣＭ）接受美托洛尔治疗，治疗后心功能改善，血浆ＮＥ下降，ＩＣＤ２５下降。本结果显示：交感神经系统的过度兴奋在ＤＣＭ心衰的发病机理中，起不良影响。

We measured NE,isoprenaline sensitlvity test,LVEF,CO,CI,SV in 27 patients with congestive heart failure from dilated cardiomyopathy, Results show:NE related negatively to LVEF,SV,CO,CI;IcD25 related negatively to LVEF,SV,CO,CI,and NE related to ICD25. After treated with metoprolol,10 patients'cardiac function improved,NE and ICD25 decreased. We conclude:over excitation of sympathetic;system may be a bad omen in congestive heart lailure from dilated cardiomyopathy。