摘要
既刻早期基因Ｃ－ｆｏｓ被作为是神经元兴奋性的一个标志。本实验利用Ｆｏｓ蛋白的免疫组织化学方法在杏仁核点燃癫痫动物模型上观察了癫痫发作后脑内Ｃ－ｆｏｓ蛋白的变化，结果表明致痫时海马部位见到较多的Ｃ－ｆｏｓ表达。提示：杏仁核点燃致痫能引起脑内某些部位Ｃ－ｆｏｓ的表达。
Expression of the immediate-early gene c-fos has been advanced as a marker of neuronal ativity in the nervous system. C-fos proteins were visualized immunohistochemically in the brain of rats after seizures induced by amygdala-kindled. Two hours following seizures there was evident expression of C-fos proteins in the hippocampus.The results Suggest that seizures can induce C-fos proteins in some nuclei.
出处
《南通医学院学报》
1995年第2期171-172,共2页
ACTA Academiae Medicinae Nantong
关键词
C-FOS
FOS蛋白
癫痫
杏仁核点燃
immediate-early gene C-fos
C-fos proteins
seizure amygdala-kindled
