128对不育夫妇血清、精浆抗精浆免疫抑制物抗体与精液检查关系的分析

AN ANALYSIS ON THE RELATIONSHIP BETWEEN ANTISPERM ANTIBODIES IN SERUM AND SEMINAL PLASMA AND SEMER EXAMINATION OF 128 IN FERTILE COUPLES

我们检测了８９对生育夫妇和１２８对不育夫妇血清、精浆中抗精浆免疫抑制物抗体（ＳＰＩ—Ａｂ）的水平。结果表明，不育夫妇血清、精浆ＳＰＩＭ—Ａｂ的水平和检出率均明显高于生育组（Ｐ＜０．０１）；精浆ＳＰＩＭ—Ａｂ水平增高者的精子密度、精子活率、精子运动速度和ＳＰＩＭ活性均明显降低（Ｐ＜０．０１）。提示：ＳＰＩＭ—Ａｂ水平增加可能影响生育。

The levels of anti - SPIM antibodies (SPIM -Ab) in serum and seminal plasma were determined in 217 married couples (fertility:89,infertility:128). The resultsshowed that the content and positive rate of serum and seminal plasma SPIM - Ab in the infertile couples were all significantly higher than in the fertile couples (P<0.01).The sperm desity, sperm viability, sperm movement velocity and SPIM activity were decreased evidently (P<0.01),when the level of APIM--Ab in seminal plasma was higher.This study indicated that the elevation of SPIM - Ab level may influence fertility.