解脲支原体在生精细胞中的定位研究

STUDY ON THE LOCATION OF UREAPLASMA UREALYTIUM INSIDE ANDROGONES

用ＨＲＰ－兔抗ＵＵ抗体进行精液中生精细胞ＵＵ定位研究。不育和妻子习惯性流产男性生精细胞ＵＵ定位阳性率分别为４０％（１１３／２８４）和４２％（３５／８３）；ＡｓＡｂ阳性和阴性患者，生精细胞ＵＵ阳性率分别为４４％（３８／８３）和３０．６％（３０／９５）；精子密度低于２０×１０＾９／Ｌ的少精子症患者，生精细胞ＵＵ定位阳性率高达７６％（３３／４５）；四环素类药物美满霉素能有效抑制ＵＵ生长。

A study on the location of Ureaplasma Urealyticum(UU) inside androgones of sperm of infertile males was performed using rabbit anti-UU antibody labeled with horse radish pero-xidase (HRP). The results showed that the positive rates of location of UU inside androgones were 40%(113/294) and 42%(35/83) respectively in the infertile males and the males whose wives had a history of habitual abortion. The positive rates of UU were 44% (38/83) and 30. 6%(30/95) in the patients with positive and negative antisperm antibody respective-ly. A high positive rate of location of UU(76%) was found in the infertile males with oligospermia (20 × 109/L). The medicines of tetracyclinic class such as minomycin were able to inhibit the growth of UU effectively. These medicines could induce the positive location of UU to become them negative and improve the fertility.