乙氧硬化醇治疗严重食管和胃底静脉曲张出血的疗效观察

EVALUATION OF SCLEROTHRAPY TREATING SERIOUS ESOPHAGO-CARDIAC VARICEAL BLEEDING WITH AETHOXYSKLER

本文报告我院对４５例严重食管和胃底静脉曲张破裂出血的患者，用１％乙氧硬化醇血管内注射治疗即硬化疗法（Ａ组），并与内科药物组（Ｂ组）和手术治疗组（Ｃ组）的疗效进行对比。结果Ａ组止血率达９８％，而再出血率Ａ组为１５％，Ｂ组６９％，Ｃ组３２％，三组比较：Ａ组明显低于Ｂ组（Ｐ＜０．０１），与Ｃ组无明显差别（Ｐ＞０．０５）。随访追踪观察：Ａ组５年存活率为７９％，Ｂ组为１９％，Ｃ组为７３％，Ａ组明显高于Ｂ组（Ｐ＜０．０１），与Ｃ组无明显差异（Ｐ＞０．０５）。

Fourty five cases of cirrhosis with serious esophago-cardiac variceal bleeding were treated with intra-variceal injection of 1 % Aethoxysklerol(Group A) ,with other two therapeutic methods as control 52 patients were received with medicine(Group B) ,and 38 patients were received with shunt surgery(Group C). The results showed that the hemostatic rate in acute bleeding was 98% in Group A. The rebleeding rate in the three groups was respectively 15%, 69% and 32%,indicating that the hemostatic rate in group A was obviously lower than in Group B (P < 0. 01) , and had no statistically significant difference (P> 0. 05 ) with group C. Five years survival rate in Group A were 79%, 19% in Group B and 73% in Group C,Group A was significantly higher (P<0. 01 )than Group B, but no statistical difference (P>0. 05)with Group C.