摘要
应用四氯化碳法制作大鼠肝硬变门脉高压症模型。采用￣（９９ｍ）Ｔｃ－甲氧基异丁基异腈经直肠－门脉放射性核素成象法对８例肝硬变大鼠和８例对照大鼠的门脉系统侧支循环进行了研究。结果表明：肝硬变组门体分流率（ＳＩ∶２０．０±１１．８％）明显高于对照组门体分流率（ＳＩ：７．７±８．２％）（Ｐ＜０．０１），ＳＩ与门静脉压力之间的相关关系无统计意义（ｒ＝０．２９，Ｐ＞０．０５）。
A rat model of liver cirrhosis and portal hypertension was established by-using
CCl_4,States ofportal circulation in 8 rats with liver cirrtiosis and 8 control subjects was
evaluated by ￣(99m)Tc-MIBI per-rectal-portal radionuclide imaging. The results were :The
SI(shunt inex)was significantly higher in rats withliver cirrhosis(20.0±11.8%)than in control
subjects(7.7±8.2%)(P<0.01)。But there was no definatecorrelation between SI and portai
pressure(r=0.29,P>0.05).
出处
《内蒙古医学院学报》
1995年第1期39-41,共3页
Acta Academiae Medicinae Neimongol
基金
美国中华医学基金
关键词
放射性
核素成象
肝硬变
门脉系统分流
liver cirrhosis
portosystemic shunt
radionuclide imaging
technetium-99m-hexakis-2-methoxy-2-isobutyl-isonitril
rats
