摘要
本文报告了20例小儿克山病尸检例心肌改变的光学与电镜的定位观察。亚急型克山病急性损伤区的心肌凝固性坏死是由于肌丝的过度收缩和透明变性,心肌线粒体异位和钙化的结果。广泛空泡变性区多为肿胀、退化和囊泡化的线粒体,同时肌丝逐渐溶解,消失。在光学显徵镜下慢型克山病心肌的基本改变主要是修复、治愈和瘢痕形成及不同程度心肌肥大,远离斑痕灶部位的电镜所见为肌原纤维粗细不等,排列不规则,少数肌原纤维离散、断裂,线粒体数目明显增多,作者也讨论了心肌结构改交与功能的关系及其心肌病变的发生机理。
This paper reports localization observation of the myocardial changes in 20 autopsied cases with children Keshan disease under light and electron microscope. Under light microscope basic changes of the myocardium in chronic Keshan disease were mainly repair cure formed scar of the myocardium, and varing degrees of myocardial hypertrophy. The different thicknees, irregular arrange of the myofibril and dispersion interupt of a few myofibril were found far from myocardial scar area under electronmicroscope. The number of cardiac mitochondrias were obviously increased. The pathogenesis of the myocardial lesion and the relationship between the structural change and function are preliminarily discuss-
出处
《中国地方病防治》
北大核心
1989年第3期133-135,共3页
Chinese Journal of Control of Endemic Diseases
