急性黄疸型肝炎284例血清学分析

Serological Analysis of284 Patients with Acute Icteric Hepatitis

应用ＥＬＩＳＡ法对２８４例急性黄疸型肝炎（急黄肝）患者的血清标本回顾性地检测了甲型肝炎病毒（ＨＡＶ）、乙型肝炎病毒（ＨＢＶ）、丙型肝炎病毒（ＨＣＶ）、丁型肝炎病毒（ＨＤＶ）及戊型肝炎病毒（ＨＥＶ）感染标志。结果，各种肝炎病毒单一感染占７９．６％，重叠感染占１８．７％（其中二重感染１７％，三重感染０．７％，四重感染１．０％）；各种肝炎病毒的检出率依次为：ＨＡＶ５８．８％＞ＨＢＶ３６．６％＞ＨＥＶ１１．３％＞ＨＣＶ１０．９％＞ＨＤＶ２．１％。提示，在我国ＨＡＶ和ＨＢＶ感染可能是急黄肝的最主要病因，单纯甲肝、单纯乙肝及甲乙混合感染可能是急黄肝的主要类型。

Using enzyme-linked im- munoassay,hepatitis A virus(HAV)、hep- atitis B virus(HBV)、hepatits C virus(HCV) 、hepatitis D virus(HDV)and hep- atitis E virus(HEV)markers were deter- mined in 284 patients with acute icteric hepatitis(AIH ).The positive rate of sin- gle infection in various hepatitis virus was 79.6%,superinfection was 18.7%(of wich ,double infection 17%, three- fold infection 0.7%, four- fold infection 1.0%)The positive rates of various hep-atitis virus markers in these patients were in orde,of HAV(58.8%)>HBV(36.6%)>HEV(11.3%)>HCV(10.9%)>HDV(2.1%).The results suggested that AIH might be caused mainly by HAV and HBV infection. Simple hepatitis A、simple hep- atitis B ,and coinfection of hepatitis A and Bmight be main clinicaI types of AIH.