海洋生物提取物“KEMH”研究──对57例体外培养不同人癌细胞的杀伤作用

STUDY ON MARINE BIOLOGICAL EXTRACT“KEMH”──THE CYTOTOXIC EFFECT ON DIFFERENT KINDS OF THE HUMAN CANCER CELLS VITRO CULTURED IN 57 CASES

报导一种海洋生物提取物“ＫＥＭＨ”对５７例体外培养的不同人癌细胞杀伤作用的实验。结果表明：“ＫＥＭＨ”对体外培养的人癌细胞有很强的杀伤作用，癌细胞对“ＫＥＭＨ”的敏感度总有效率达５５．４％。本文以１０例以上者按不同癌细胞对“ＫＥＭＨ”的敏感度进行分组统计，指出“ＫＥＭＨ”对肺癌细胞的杀伤率最高，为９４％；对乳癌细胞为６８％；对胃癌细胞为５３．１％．与对照组比较，Ｐ值差异性显著。与常规较有效的抗癌药环磷酰胺，盐酸阿霉素等五种药物比较，“ＫＥＭＨ”比这五种药物对癌细胞具较高的杀伤作用。

The cytotoxic effect of "HEMH",a kind of marine biological extract, on thehuman cancer cells vitro cultured is reported. The results show that "KEMH"has astrong cytotoxic effect on the human cancer cells vitro cultured. The sensiblity ofall cancer cells to "KENH"is 55. 4%. The killing rates of "KEMH"for differentcancer cells are as follows: 94% for lung cancer, 68% for breast cancer, and 53. 1 %for gastric carcinoma. The disparity of the P value iS significant compared with theOD values of the control groups, "KEMH"also demonstrates a higher lethal effecton cancer cells compared with 5 kinds of effective anticancer drugs such as cyclophosphamide and adriamycin.