HBV感染者血中大颗粒淋巴细胞的测定

DETERMINATION OF LARGE GRANULE LYMPHOCYTES IN BLOOD OF PERSONS INFECTED WITH HEPATITIS B AND ITS SIGNIFICANCE

分５组测定了乙型肝炎病毒（ＨＢＶ）感染者血中大颗粒淋巴细胞（ＬＧＬ）的含量，每组各３０例。其中①组：乙型肝炎表面抗原（ＨＢｓＡｇ）、ｅ抗原（ＨＢｅＡｇ）和核心抗体（ＨＢｃＡｂ）均为阳性；②组：为ＨＢｓＡｇ和ＨＢｅＡｇ阳性者；③组：为ＨＢｓＡｇ阳性、抗ＨＢｅ和抗－ＨＢｃ阳性者；④组：为抗－ＨＢｓ阳性者；⑤组：为抗ＨＢｓ和抗－ＨＢｅ阳性者。并且与对照组进行比较。结果表明，①组的ＬＧＬ含量明显高于对照组，差异有极显著性（Ｐ＜０．０１），②组和③组的ＬＧＬ含量也明显高于对照组，差异有显著性（Ｐ＜０．０５）。提示人体感染ＨＢＶ后血中的ＬＧＬ含量显著增高，可能有利于ＨＢＶ的清除。

The contents of large granule lymphocytes(LGL) were determined in 5 groups of persons infected with the hepatitis B virus(HBV),each group consisting of 30 persons.The result showed that Group 1 was positive for surface antigen(HBsAg),e antigen(HBeAg) and core antibody(HBcAb);Group 2 positive for HBsAg and HBeAg;Group 3 for HBsAg,HBeAb and HBcAb;Group 4 for HBsAb;Group 5 for HBsAb and HBeAb.Comparison made between the 5 groups and the control group showed that the LGL contents were significantly higher in Group 1 than in the control group(P<0.01) and so were the LGL contents in Groups 2 and 3(P<0.05).The above suggests that after infection by the hepatitis B virus,the number of LGL increases obviously in the body and that may be helpful for the elimination of HBV.