55例老年慢性肺心病急性加重期β_2微球蛋白测定的临床意义

THE CHANGE AND CLINICAL SIGNIFICANCE OF BLOOD β_2-microglobulin In ACUTE EXACERBATION OF 55 SENILE PATIENTS WITH COR PULMONALE

本文采用放射免疫法测定了55例老年肺心病急性加重期患者血及尿液中β2微球蛋白（β2－MG）含量的变化。结果显示，肺心病急性加重期病人中，绝大多数血尿β2－MG不同程度增高（P＜0．05）。较血BUN、Cr改变出现早而灵敏度高。是较早了解肺心病急性加重期肾功能损害较灵敏而可靠的方法。

This paper reported the changes of blood and urine β2-microglobulin in acute cxacerbation of 55 senile patients with cor pulmonale. The radioimmunoassay(RIA) was used in these cases. The results showed: the contents of blood and urine β2 -microglobulin had increaed in most of the patients (P<0. 05), the changes appeared early and were more sensitive than BUN and Cr. This is a good method to understand the injury of the kidney function in the patients with cor pulmonale.