摘要
高效液相色谱法测定马吲哚片含量徐朝霞,唐树荣(江苏省涟水县制药厂涟水223400)1前言马吲哚片收载于美国药典 ̄[1]中,是一种较好的减肥药,国内也研制成功,已经投产。美国药典采用高效液相色谱法(HPLC)测定含量,以盐酸阿米替林为内标,所费时间较长...
he present paper deals with the HPLC method used for the determination of mazindoI tablets,The op-timum conditions were as follows:ZORBAX CN column(4.6mn× 25cm);methanol/0.0l mol/L ammoniumdibasic phosphate buffer(8:2)as mobile phase and UV-254 detection. The proposed method is simple andrapid without the need of any preliminary separation,The results obtained are satisfactory both in recovery and precision.
出处
《色谱》
CAS
CSCD
北大核心
1995年第1期72-73,共2页
Chinese Journal of Chromatography
关键词
HPLC
马吲哚
减肥药
磺胺
high performance liquid chromatography ,mazindol, mazindol tablet