摘要
高效液相色谱法测定枸橼酸他莫昔芬片的含量刘玉华，李太平（丹东市第一医院药剂科丹东１１８０００）（丹东市药品检验所丹东１１８００２）１前言枸橼酸他莫昔芬片为新的治疗晚期乳腺癌的药物，现已广泛应用于临床。其质量标准￣［１］中对本品的含量测定采用紫外（ＵＶ...
n RP-HPLC method for the quantitative determination of contents of tamoxifeni citrate tablets was devel-oped.The operating conditions are as follows:CN column,250mm×4.6mm;mobile phase:mixture of methanol-water-glacial acetic acid-sodium heptyl sulfonate(340:160:1: 0.5);internal standard,trimethoprim;detectionwaveiength,254nm;and flow rate,0.6mL/min,Coefficient of variaion was1.1%,This method is simple and re-liable.
出处
《色谱》
CAS
CSCD
北大核心
1995年第6期483-484,共2页
Chinese Journal of Chromatography
