HBV感染者及携带者血清sIL－2R含量测定及意义探讨

Study on serum sIL-2R contents and signeficance for HBV infected persons and carriers

本文应用双抗体夹心ＥＬＩＳＡ法检测了１０８例ＡＶＨ，ＣＡＨ，ＣＰＨ、ＨＢＶ健康携带者和２２例正常人血清ｓＩＬ－２Ｒ含量，并分析了ｓＩＬ－２Ｒ与ＡＬＴ的关系。结果：ＡＶＨ、ＣＡＨ患者血清ｓｌＬ－２Ｒ均显著高于正常对照组（Ｐ＜０．０１），并与血清ＡＩＴ水平呈正相关。而ＣＰＨ及ＨＢＶ健康携带者ｓＩＬ－２Ｒ水平与正常对照组比较无显著差异（Ｐ＞０．０１），结果捉示：血清ｓＩＬ－２Ｒ的异常升高与乙型肝炎的活动性有关。

he serum contents of sIL-2R were measured in 108 cases with acute viral hepatitis( AVH).chronic active hepatitis( CAH)and chronic persistent hepatitis(CPH),HBV carriers and 22 controls by using ELISA。 The relationship between the contents of sIL 2R and ALT was analysed. The results revealed that the serum sIL 2R contents were signifi- cantly higher in the cases with AVH and CAH than those in controls (P<0.01)and corre- lated well with ALT activity, There was no significant statistical difference among the cases with CPH,carriers and controls.It suggested that abnonnally increased sIL-2R contents may be related to hepatitis B disease activity。