摘要
对４６例慢性肾功能衰竭（肾衰）患者同步检测了细胞免疫功能和微量元素，并选３０例正常人做对照。结果表明，慢性肾衰患者ＯＫＴ３、ＯＫＴ４、ＯＫＴ４／Ｔ８明显低于正常对照组（Ｐ＜０．０１）。血清微量元素锌、铁、铜低于正常对照组（Ｐ＜０．０５～０．０１），血清铝较正常对照组明显升高（Ｐ＜０．０１），血清锌与ＯＫＴ４／Ｔ８呈正相关（ｒ＝０．３２６６，Ｐ＜０．０５）。提示慢性肾衰患者细胞免疫功能降低，微量元素锌、铁、铜含量降低，铝含量升高，锌含量与细胞免疫功能之间呈正相关关系。
Synchronous measurements of cellular immune function and trace elements were taken in 46 cases of chronic renal failure (CRF) patients. The results were stated as follows: (1) Obvious decrease of OKT3. OKT4. OKT4/T8 was found in CRF (P<0.01) . (2)Obvious decrease of serum Zn、Cu、 Fe ( P<0.05-0.01), obvious increase of serum Al (P<0.01 ) were found in CRF. ( 3 ) Serum Zn were proportional to OKT4/T8 (P<0.05 ) .These results indicated that cellular immune function was decreased in CRF. Serum Zn、 Fe、 Cu were decreased, otherwise serum Al was increased in CRF, cellular immune function was closely related to serum Zn.
出处
《山东医科大学学报》
1995年第4期294-297,共4页
Acta Academiae Medicinae Shandong
关键词
肾功能衰竭
细胞免疫
微量元素
单克隆抗体
Kidney failure, chronic
Immunity, cellular
Trace elements
Antibodies, monoclonal
