助动车尾气的Ames试验

Ames Test of Auto-cycle Exhaust Particulates

采用鼠伤寒沙门氏菌Ames试验,对国产及进口的3种牌号助动车(迅达.永久、霸伏)排出的尾气进行研究。结果表明,3种牌号助动车排出尾气的颗粒提取物均可引起TA_(98)回变菌落数的增加,较阴性对照(DMSO)有明显差异,各浓度组均有剂量—反应关系的存在,说明这些颗粒提取物含有能引起移码型突变的物质。体外代谢活化系统S_9对试验结果没有明显影响,说明致突变物既含间接致突变物,也含直接致突变物。

Study of the mutagenicity on various auto-cycle exhaust particulates by Ames test has been conducted. The results showed that all of the auto-cycle exhaust particulates were mutagen of TA98 strain and existed the dose response relationship. The exhaust particulates are indirect mutagenic factor as well as direct mutagenic factor and frame-shift mutagens.