豚鼠血清IgG含量的研究

Study on the Level of Serum IgG in Guinea Pig

采用单向琼脂免疫扩散法，测定Ｚｍｕ－１：ＤＨＰ品系豚鼠的血清ＩｇＧ含量。从１５～７０日龄起，血清ＩｇＧ水平逐渐递增，７０日龄后趋于平稳或稍有下降。血清含量的变异系数随日龄增加而递减。该品系豚鼠常用日龄（３５ｄ）或体重（３００ｇ）的血清ＩｇＧ正常值为５．３７ｍｇ／ｍｌ。在不同日龄ＩｇＧ的含量与性别一般无关。Ｚｍｕ－１：ＤＨＰ品系豚鼠血清ＩｇＧ含量水平与其他品系比较，具有稳定的变化规律，个体间差异较小，说明该品系豚鼠的遗传性和免疫反应性较为一致。

he level of serum IgG in conventional Zmu-1:DHP guinea pig was detected by single radial immunodiffusion. The level was increased with age from 15-70 days, and tended to be steady or declined slightly thereafter. The level of serum IgG of the strain at the age of 35 days (about 300 g body weight) was 5.37 mg/ml. Generally there was no significant difference in sex. As compared with the purchased strain. the level of serum IgG of Zmu-1:DHP guinea pig bad a more steady Pattern and a less difference among individuals.