摘要
利用免疫方法制作动物模型及中药组方对实验性溃疡性结肠炎(简称UC)的免疫指标观察。结果表明该方能有效地抑制异常增高的体液免疫(IgG)而提高功能低下的细胞免疫(Ea—RFC、Et—RFC、LTR)纠正比例失调的CD_4/CD_8水平,疗效明显高于柳氮磷胺嘧啶(SASP)(P<0.05)。
Forty SD white rats were used to test their immunologic functions after being made ulcerative colitis and were devided into: group 1, cured with herbal enemas (n= 10) ; group 2, cured with SASP enemas (n= 10) ; group 3, cured with normal saline enemas (n=10); group 4; cured with nothing (n = 10). The results showed that the curative effect of the group 1 was evidently superier to the group 2- It was suggested that herbal enemas could effectively correct the pathologic change of colon mucosae. The research had also found out that herbal enemas could not only sharply reduce abnormal IgG, but also strengthen the immunologic function of cells probably, raise the levels of Ea-RFC,Et-RFG LTR and adjust the abnormal proportion of CD4/CD8. Thus, the herbal enemas effect is better than SASP enemas' and is effective therapy(P<0. 05).
