摘要
在纯化人卵巢抗原的基础上，建立了检测血清抗卵巢抗体、游离卵巢抗原及其特异免疫复合物的ＥＬＩＳＡ方法。发现早闭经患者这三顶指标的阳性率都有显著升高。提示抗卵巢抗体可能参与卵巢免疫损伤。
On the basis of the purification of ovarian antigens, enzyme linked immunosorbentassay (ELISA)was established for quantitative determination of antiovarian anti- bodies, free ovarian antigens and their specific immune complex in the serum. The re-sults of clinical studies showed that there were significantly higher positive rates ofthe three indexes in the patients with idiopathic premature menopause. It suggests thatantiovarian antibodies and their immune complex may play a role in immune injuryof the ovary
出处
《上海医学》
CAS
CSCD
北大核心
1995年第6期328-330,共3页
Shanghai Medical Journal
关键词
抗卵巢抗体
抗原
免疫复合物
闭经
Antiovarian antibodies
Ovarian antigens
Immune complex
Premature menopause
