摘要
用局限性损毁和刺激垂体的方法，观察了垂体与下丘脑弓状核（ＡＲＣ）在痛觉调制中的关系。实验结果表明，损毁垂体中间叶和前叶能降低基础痛阈，取消刺激ＡＲＣ即刻出现的镇痛作用。刺激垂体的相同部位能提高基础痛阈，并出现有一定潜伏期的镇痛作用。这个镇痛作用能被损毁ＡＲＣ所阻断。
Relationship between pituitary gland and hypothalamic arcuate nucleus (ARC) in the modulation of pain threshold was investigated in Wistar rats with method of focal lesion and stimulation of pituitary gland. Experimental results indicated that electrolytic lesion of the pituitary intermediate and anterior lobes resulted in a decrease of pain threshold and disappearance of the analgesia immediately produced by ARC stimulation. Stimulation of the same area of pituitary gland could induce a delayed analgesia,which could be blocked by ARC lesion.
出处
《生理学报》
CAS
CSCD
北大核心
1995年第5期505-509,共5页
Acta Physiologica Sinica
基金
国家自然科学基金
关键词
痛觉调制
损毁
刺激
垂体
下丘脑
弓状核
lesion
stimulation
pituitary gland
hypothalamic arcuate nucleus
pain threshold
pain modulation
