摘要
Ｃａ２＋能诱发ＣＬ／ＰＣ脂质体的聚集，漏出及进一步的融合。其作用大小随着Ｃａ２＋浓度的增高而增强。吸收、荧光和冷冻断裂电镜等方法所得结果证明了这一点。ＢＰＰ抑制由Ｃａ２＋诱发的ＣＬ／ＰＣ脂质体的聚集和融合，其作用的大小随ＢＰＰ的增加而增大。上述三种方法从不同角度都给出了同样结果，肯定了ＢＰＰ抑制ＣＬ／ＰＣ脂质体由Ｃａ２＋诱发的聚集和融合作用。
The induction of aggregation. leakge and fusion of the CL/PC liposomes by Ca2+ was studied with the absorption fluorescence and freeze-frature electren micrographs. BPP inhibits the aggregation and fusion of CL/PC liposomes. These inhibition effects increase with the increace of BPP concentration.The mechanism of inhibition of BPP on aggregation and fusion of CL/PC liposomes may be related to the inhibition of the Lα→ H11 transition of liposomes.
出处
《生物物理学报》
CAS
CSCD
北大核心
1995年第1期25-30,共6页
Acta Biophysica Sinica
基金
国家自然科学基金
