摘要
从非复制性病毒(家禽痘、野鸟痘、痘苗和人类腺病毒)载体重组活疫苗、腺病毒载体重组口服活疫苗和杆状病毒载体重组亚单位疫苗三方面,评述了以病毒为表达载体的基因工程疫苗近年研究取得的重大进展。
The update important
advances,existing questionis,developing countermeasures application
prospects of virus-vectored vaccines have been critically re-viewed
from the following three aspects:(1)Nonreplicating
fowlpoxvirus,canarypoxvirus,vaccinia cirus of human
adenovirus-vectored live vaccines their immunity;(2)Live
adenovirus-vectored vaccines their immunity; and(3)
Bacularvirus-vectored subunit vac-cines tyeir immunity.It is an
update trend in genetically-engineered vaccines that the
virus-vectored vaccines have come of age.
出处
《实验动物科学与管理》
1995年第3期37-42,共6页
Laboratory Animal Science & Administration
关键词
疫苗
病毒载体
载体疫苗
Recombinant
vaccines
Viral vectors
Immunity
Non-replicating
Replicating
Avipoxvirus
Adenovirus
Bacularvirus A
Visiting Scholar at the National Laboratory of Molecular Virology
Genetic Engineering,Institute of Virology,Chinese Academy of
Preven