食管癌手术前后SOD动态变化的临床观察

Clinical Observation on Dynamic Changes of Serum Superoxi de Dismutase (SOD ) in Patients with EsophageaI Cancer pre-and postoperation

本文报告２０例食管癌患者手术前的超氧化物歧化酶（ＳＯＤ）动态变化的临床观察结果，提示：（１）术前总ＳＯＤ与术中和术后比较，有显著差异或非常显著差异（ｐ＜０．０５或Ｐ〈０，０１）；（２）术中ＣｕＺｎＳＯＤ明显高于术前（ｐ＜０．０１）；（３）ＭｎＳＯＤ在整个围术期无明显变化（Ｐ＞０．０５）。作者对这些变化的临床意义进行了讨论。

In 2 0 Cases of esophageal cancer , determination has been made of the dynamic changes of totalSOD ,CuZnSOD and MnSOD pre-and postoperation. The results indicated that :(1) Total SOD was higher beforoperation than that during and after operation(P<0. 05 or P < 0.01 ).( 2)The levl of CuZnSOD during operationwas much higher than that before operation ( P<0.01).(3)There was no obvious changes in MnSOD during peri- operative period ( P>0.05).The reasons and clinical significance of these changes are discuased.