新菌灵与美欧卡霉素对照治疗小儿以呼吸道感染为主的疾病

Comparative efficacies of cefuromycin and miocamycin in children with upper respiratory tract infections

目的探讨小儿呼吸道感染性疾病的药物治疗。方法呼吸道感染性疾病等患者５４例，随机分为治疗组和对照组。治疗组２７例，用新菌灵（ＣＸＭ－Ａ）治疗。＜５岁服ＣＸＭ－Ａ１２５ｍｇ，每日２次，＞５岁服ＣＸＭ－Ａ２５０ｍｇ。每日２次。对照组２７例，用美欧卡霉素治疗，剂量为每公斤体重３０ｍｇ，分（３～４）次口服。结果治疗组总有效率为９６％，而对照组为８１．４８％（Ｐ＜０．０５）。新菌灵治疗上呼吸道感染、气管炎及支气管炎、肺炎的有效率分别为１００％、１００％和５０％。结论新菌灵治疗小儿呼吸道感染性疾病效果优于美欧卡霉素。

Objective To Study the drug treatment toward Children's respiratory tract infectious disceses.Methods There are 54 patients with respiratory tract infectious discases.They were divided into two groups(therapeutie and control group)randomly.The thera-Peutic group(27 patients)were treated with cefuromycin,125 mg,twice a day for the younger than 5 years old,and 250mg for the older than 5years old.The Control group were treated with miocamycin,30 ma.d-1,it should be taken,3 to 4times a day.Results The effective rate was 96% in therapeutic group and 81.48% in control group (P<0.05).The effective raies of the treatment with cefuromycin toward upper respiratory tract infection, trachitis and bronchitis,and Peumonia are 100%,100% and 50% respectively.Conclusion The therapeutic effect of ceu,romycin is better than that of miocamycin,when treating children's respiratory tract infectious diseases.