免疫和生化指标的检测在血吸虫病临床的应用

DETECTION OF IMMUNOLOGICAL AND BIOCHEMICAL MARKERS ON THE SCHISTOSOMIASIS AND THEIR CLINICAL APPLICATION

１３５例各个不同时期的血吸虫病患者检测７项免疫及生化指标（ＡＮＡＥ、ＲＢＣ－Ｃ３ｂＲＲ，ＲＢＣ－ＩＣＲ，ＣＩＣ，Ａ／Ｇ，ＨＰＴ及ＡＤＡ），并以正常人对照，结果显示慢血组（３０例）有３项不正常，肝脾肿大组（３３例）有６项不正常，晚血组（７２例）７项均不正常。可见肝脾肿大组的免疫、生化指标的改变比慢血组更接近于晚血，将此型血吸虫病列为晚血范畴更为合理，称晚血早期。Ａ／Ｇ，ＡＤＡ，ＨＰＴ及ＲＢＣ－Ｃ２ｂＲＲ４项检测指标可作为晚血早期判断的依据。

Seven indices of immunological and biochemical tests (ANAE, RBC-C3bRR, RBC-ICR, A/G, CIC, HPT and ADA) were determined from 135 patients with various stages of schistosomiasis japonica and normal individuals.The results showed three of seven indices abnormal in the group of chronic schistosomiasis (30 cases).Six abnormal in the group of hepatosplenomegaly (33 cases) and all seven abnormal in the advanced schistosomiasis group (72 cases). The investigetion suggested that the changes in the group of hepatosplenomegaly schistosominsis are even closer with advance patients than in chronic patients.Therefore, it is suitable to classify the patients with hepatosplenomegaly group into advanced schistosomiasis, and to call them early stage of advancwed schistosomiasis,HPT,ADA A/G and RBC-C3b RR may act as the indices of early dingnosis of advanced schistosominsis.