室内繁殖和野生东方田鼠感染日本血吸虫的比较

EXPERIMENTAL INFECTION OF SCHISTOSOMA JAPONIOUMIN WILD AND LABORATORY MICROTUS FORTIS

用室内繁殖第三代乐方田鼠和野生东方田鼠进行了日本皿吸虫人工感染比较试验。结果表明，东方田鼠通过室内繁殖三代继代后，仍对日本血吸虫感染存在抵抗力，虫体不能在其体内生长发育成熟，但日本血吸虫在室内繁殖第三代东方田鼠体内较野生既体内生长发育为好。童虫在野生东方田鼠肺脏内的停留时间较室内繁殖田鼠肺脏内长２天，而日本血吸虫在野生东方田鼠体内生长发育停滞时间要较室内繁殖者早２天，此外，室内繁殖鼠体内的虫体较野生鼠体内同龄虫体大。野生鼠肝脏表面虫体炎性结节较室内繁殖鼠早出现１天，消退亦早４天。日本血吸虫在野生鼠体内消亡亦较室内繁殖者早。

The route, duration of migrating schistosomula, and the growth and development of larva within wild and third generation laboratory M. fortis experimentally infected with S. japonicum have been studied. The results showed that no adult worm was developed in both kind of M.fortis, but the schistosomula grew a little better in M. fortis bred in lab than in wild ones.