国产人工合成材料修补腹壁缺损在组织中的耐受性

Tissue tolerance of domestic prosthetic materials in repair of largc defects of the abdominal wall

人工合成材料周围组织中成纤维细胞／炎性细胞比率是评价材料在组织中耐受性最佳标准：本实验利用这个标准通过对动物实验对国产四种人工合成材料：碳纤维网、涤纶布、硅橡胶膜和丝绸在组织中耐受性对比研究结果是：涤纶布在组织中耐受性最佳，其次是碳纤维网，最差的是丝绸材料。

The experimental study in rabbit is to compare the tolerance of four domestic prosthetic materials: carbon fiber mesh、 siliconized velvet、 silk and dacron cloth in the tissue.The four prosthetic materials were implanted in the subcutaneous tissue of the abdominal wall of rabbits. These implants and their surrounding tissues were excised after operation at second、 fourth, eighth and twelfth weeks.using “LUEX一F’picture analysis machine to count the fibroblastic cells and inflammatory cells in sur-rounding tissues of each material and counts fibroblastic/ inflammatory cell ratio(FC / IC ratio). The result shows that fibroblastic cell reaction elicited by carbon fiber mesh is greatest in the four prosthetic materials,dacron cloth the second.The inflammatory cell reaction elicited by silk is greatest,second iS carbon fiber mesh,dacron cloth the least. The tolerance of dacron cloth knew by FC/IC ratio in tissueis the best in the four prosthetic materials, while sick is the worst. Studying the to lerance of four domes-tic prosthetic materials in the tissue may be a basis for selecting the best prosthetic material.