何为免疫性不育？

Ureaplasma urealyticum infection and male infertility

何为免疫性不育？我们知道精子是男性成年后由睾丸产生的，习惯称其为隐蔽抗原。在男性，当前列腺炎、精囊腺炎和输精管炎、或睾丸受腮腺炎病毒感染、受外伤、高温或化学药物的损害时，都可以破坏血睾屏障的完整性，使精子进入血流；在女性，由于阴道炎、盆腔炎或经期性交...

Double-antibody sandwich ELISA was used for the detection of ureaplasma urealyticum,and was compared with classical culture method.The positive rates were 10.3%by ELISA and 7.7%by classical culture respectively in the seminal plasma of 39 fertile men,while they were 35.4%and 31.7%respectively in the seminal plasma of 164 infertile men.From these results,we found the difference of positive rates was significant in fertile and infertile men,and their identity rate was 86.5%. The positive rates of ureaplasma urealyticum were 69.2%and 56.5%respectively in the infertile men with their sperm morphological abnormality over 30%,and in those with their sperm density lower than 20 million/ml. Ureaplasma urealyticum infection may lead to male infertility due to the morphological and functional abnormalities of sperm caused by it.