摘要
采用华蟾素治疗慢性乙型肝炎３３例（对照组３２例）。治疗组除与对照组应用相同治疗外，加用华蟾素４ｍＬ肌注１次／ｄ，４５ｄ为１疗程。１疗程结束后治疗组ＨＢｅＡｇ和ＨＢＶ－ＤＮＡ阴转率分别为４４．８４％和３４．６１％，而对照组ＨＢｅＡｇ和ＨＢＶ－ＤＮＡ阴转率分别为７．１４％和０。提示华蟾素治疗慢性乙型肝炎近期疗效确切。
cases of chronic hepatitis B (32 cases for control) were treated by cinobufacini. The same management was used for both control and treating groups ,except an additional treatment by injecting 4 mL of cinobufacini per day intramuscularly,for the treating group. There were 45 days in one course of treatment. Afrer one course,the negative conversion rates of HBeAg and HBV-DNA in the treating group were 44. 84% and 34. 61% respectively, while in the control group they were only 7. 14% and 0 respectively. This observation suggests that short-term effect of cinobufacini is rather satisfactory for treating the chronic hepatitis B.
关键词
慢性
乙型肝炎
药物疗法
华蟾素
hepatitis B virus
hepatitis B
cinobufacini
negative conversion rate
