刺梨抗动脉粥样硬化作用与超氧化物歧化酶

THE EFFECT OF ROSA ROXBURGHII TRALL PREVENTING ATHEROSCLEROSIS AND ITS RELATION TO SOD ACTIVITY

通过动物实验，对刺梨抗动脉粥样硬化作用进行了研究。结果表明，高脂高胆固醇组动物主动脉内膜呈现明显的粥样硬化改变，ＳＯＤ活性比对照组低３７．３％，ＬＰＯ含量高出对照组３．６倍；刺梨加高脂高胆固醇组主动脉内膜仅有散在斑块，病理改变轻微，而ＳＯＤ活力高出高脂高胆固醇组约２２％，ＬＰＯ下降约４４％。提示刺梨能够提高ＳＯＤ活力，降低脂质过氧化，减少粥样化斑块的形成。

We made researches on the effects of rosa roxburghii trall of preventing atherosclerosis,It was obvious that arterosclarosis formed in the first group,SOD activity decreased by 37.3% and the level of LPO was higher than that of control by 3.6 times.In the second group,atherosclerosis was very slight and SOD activity increased than that of the first gronp by 22%,the Level of LPO decreased by 44%.The results of our study expressed that rosa rexburghii trall Can increase SOD activity,decrease Lipid Peroxidation.