摘要
喂小鼠去蛋白饲料造成小鼠蛋白质能量营养不良(PEM),用扫描电镜(SEM)和体外鸡红细胞吞噬试验观察其腹腔巨噬细胞(M)膜表面结构及吞噬功能变化。结果,随喂去蛋白饲料时间延长,小鼠体重下降,血清蛋白含量降低,M膜表面绒毛样凸起基本消失,M 的吞噬功能亦下降;改喂含17%蛋白质的饲料后,其腹腔M 膜表面结构和吞噬功能均可逐步恢复正常.提示,蛋白质缺乏造成的PEM直接导致了M 膜结构损伤和吞噬功能下降,但如及时补充蛋白质,这种损伤是可逆的.
n this study, protein--energy malnutrition(PEM) of mice was resulted in by feeding protein- free blood, then normal diet (containing 17% protein ) for these with PEM. We observedcytomembrane structure and phagocytosis of peritoneal M of the mice with PEM by means ofscanning electron microscopy(SEM) and phagocytosis-- test in vitro. The resultS showed: 1. The viili--like Protrusion on the surface of M membrane were reduced progressively up to nearly disappearalong with the weight reducing of mice with PEM. 2. The phagocytic precentage and index ofperitoneal M in mice with PEM were significantly lower than that in normal mice. 3. It could berecovered through protein supplementation in thee.
出处
《苏州医学院学报》
1995年第1期37-39,74,共4页
Acta Academiae Medicinae Suzhou
关键词
蛋白质
营养不良
吞噬功能
巨噬细胞膜结构
protein -- energy malnutrition (PEM)
sytomembrane structure of peritoneal M
phagocytosis
electron microscopy(SEM) (P. 37)