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接触性皮炎斑贴试验化妆品系列抗原的对比研究 被引量:2

A COMPARATIVE STUDY OF A COSMETICS PA TCH TEST SERIES OF ALLERGENS WITH THE EUROPEAN COSMETICS SERIES
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摘要 按照欧洲化妆品系列抗原(简称欧抗)的成分和浓度,利用国产试剂配制一套自制抗原(简称自抗),在显微镜下对自抗10种抗原颗粒分布均匀性及抗原颗粒大小这两项质量指标进行了检测,并做了动物皮肤急性刺激实验,同时与欧抗相应抗原进行了对比。结果证实,自抗已达欧抗质量水平。在临床161例患者中,欧抗化妆品系列斑试总阳性率为16.35%,其中阳性率在1%以上的有7种。 A set of our domestic allergens(DA), the cosmetics series,was prepared according to the concentrations provided by The InternationalContact Dermatitis Research Group(ICDRG).Thehomogeneity and sizes of particles of 10 kinds each of DA were tested and compared with corresponding to European allergens(EA). Finally, The Patch testing with DA and EA on the 161 patients with facial contact dermatitis was carried out. The results indicate that the quality of DA has reached the level of EA. Patch testing positive rate of European cosmetics series was 16. 35%, in which, positive rates of 7 kinds allergens are more than 1%.
出处 《天津医科大学学报》 1995年第2期1-3,10,共4页 Journal of Tianjin Medical University
基金 天津医科大学青年科研基金
关键词 接触性皮炎 斑贴试验 抗原 Patch test Contact dermatitis Allergens
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同被引文献16

  • 1李邻峰.接触性皮炎与皮肤变态反应[M].2版.北京:北京大学医学出版社,2003:80-82.
  • 2Wetter DA,Yiannias JA.Results of patch testing to personal care product allergens in a standard series and a supplemental cosmetic series:an analysis of 945 patients from the Mayo Clinic Contact Dermatitis Group,2000-2007[J].J Am Acad Dermato1,2010,63(5):789-798.
  • 3Bilcha KD,Ayele A,Shibeshi D,et al.Patch testing and contact allergens in Ethiopia-results of 514 contact dermatitis patients using the European baseline series[J].Contact Dermatitis,2010,63(3):140-145.
  • 4Li LF,Guo J,Wang J.Environmental contact factors in eczema and the results of patch testing Chinese patients with a modified European standard series of allergens[J].Contact Dermatitis,2004,51(1):22-25.
  • 5Adams RM. Occupational Skin Disease. 2nd edition. Philadelphia,USA. Saunders, 1990. 228
  • 6Fischer T, Maibach H. Patch test allergens in petrolatum: a reappraisal. Contact Dermatitis, 1984,11:224
  • 7Adams RM. Occupational Skin Disease. 2nd edition. Philadelphia, USA. Saunders,1990. 230
  • 8中华人民共和国国家标准.GB7919-87.中华人民共和国卫生部,1987.3-4
  • 9Vanneste D.Comparative study of the density of particles in suspension for patch testing. Contact Dermatitis, 1980, 6:197
  • 10North American Contact Dermatitis Group. Epidermiology of contact dermatitis in North America: 1972. Arch Dermatol,1973, 108:537

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