梗阻性黄疸血浆细菌内毒素含量观察

Observations on Bacterial Endoloxin in Serum of Obstructive Jaundice Patients

总结28例梗阻性黄疸患者,包括良性梗阻14例、恶性梗阻14例,均进行血浆内毒素检测,并行手术前后自身对照。结果显示良性黄疸和恶性黄疽组术前与术后3天、7天比较差异均有高度显著性(均P<0.01)。术后3天与术后7天两组比较,结果均无显著性差异(均P>0.05)。良性与恶性亦无显著性差异(均P>0.05)。本资料表明梗阴性黄疸病人血浆内毒素含量明显升高,经手术引流内毒素含量下降,对临床诊治有一定价值。

The purpose of study was to summarize 28 surgical cases with ohstructive jaundice which were treated in hospital. Among these 28 cases, 14 were benign, the others were malignant. The serum endotoxin levels of pre-operation and post-operation were measured respectively, then .all these data were compared with normal group. The results showed that in benign obstructive jaundice group and the malignant group .there was a remarkable difference between pre-operation and post-operation of 3 days and 7 days separately (P<0. 01). The groups of post-operation for 3 days was compared with the groups of 7 days respectively .there were no obvious difference (P>0. 05), and no evident differenes between the benign and the malignant groups(P>0. 05 ). The data indicated that serum endotoxin content in obstructive jaundice patient increased,but the endotoxin level declined after drainage operation. Thus the data were of great value to clinical treatment.