老年急性心肌梗塞患者血浆儿茶酚胺及肾素系统的变化

Changes of Activity of Catecholamine and Renin System in Elderly Patients with AMI

通过对30例老年急性心肌梗塞(AMI)患者血浆儿茶酚胺(CA)及肾素-血管紧张素-醛固酮系统(RAAS)的检测,发现去甲肾上腺素(NE)、肾上腺素(E)、多巴胺(DA)及肾素(PRA)、血管紧张素Ⅱ(ATII)和醛固酮(ALD)浓度均高于老年对照组(P<0.01),且在心功能损害时更明显。相关分析显示:血浆CA变化与PRA、ATII、ALD密切相关,提示AMI时血浆CA增高可能是激活RAAS的因素之一。

In 30 elderly patients with AMI levels of plasma catecholamine (CA),plasma renin activity (PRA) ,angiotensinII(ATII) and aldosterone (ALD) were significantly higher than those of con-trol group (P<0. 05-0. 01). The changes indicated the severity of heart dysfunction. The correla-tive analysis showed the changes of plasma CA were closely correlated with those of PRA,ATII and ALD. It indicated the changes of plasma CA during AMI may be one of factors to activate renin-angiotensin-aldosterone system(RAAS).