宫颈癌患者肾图变化及预后

The Isotope Nephrography in Carcinoma of Cervix and Its Prognostic Significance

采用１３１碘－邻碘马尿酸钠肾图法，对１１９例宫颈癌ⅢＢ期患者进行肾图检查。结果：双侧肾图明显异常１３例（１０．９３％），中度异常３２例（２６．８９％），轻度异常或正常７４例（６２．１８％）．双侧肾图明显异常组的３年生存率为３０．７７％，中度异常组为５６．２５％，轻度异常或正常组为７２．９７％，三组差异有显著性意义（Ｐ＜０．０１）。三组患者的５年生存率分别为３０．７７％，３７．５０％及６７．５７％，差异也有显著性意义（Ｐ＜０．０１）。本文提示：肾图检查可作为宫颈癌患者宫旁浸润是否累及输尿管，并造成尿路梗阻及肾功能受损的有效诊断方法，也可作为判断宫颈癌患者预后的重要指标。

I-hippuran nephrography were performed in 119 patients with stage Ⅲb,cervical caner before treatment.The results showed 13(10.93%) patients had bilateral serious abnormal isotope renogram,32(26.89%) patients had bilateral moderately abnormal isotope renogram and 74(62.18%) patients had bilateral slightly abnormal or normal isotope renogram.The three-year suvival rates were 30.77% for the patients with bilateral seriously abnormal isotope renogram,52.25% for the patients with bilateral moderately abnormal isotope renogram and 67.57% for patients with bilateral slightly abnormal or normal isotope renogram.The difference in three-year survival among the three groups of patient was statistically significant(P<0.01).The five-year survival for the three group of the patients with bilateral abnormal isotope renogram were 30.77%,37.50% and 67.57% respectively and the difference was highly significant(P<0.05).The results suggest that the isotope nephrography was a method for judging the existence of advanced malignancy involving the parametrial tissues,the ureteral obstruction and impaired renal function in cervical cancer patients,The isotope nephrography can also be used for determining prognosis of the patients.